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doi: 10.1016/S2213-8587(19)30180-9 10 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFNauckMAet al

Because GLP-1 medications often lead to smaller meals and lower overall intake, maintaining adequate vitamin D through food alone may become more difficult over time

Generally, there is a corresponding antioxidant system to equilibrate oxidation

Elevated levels of reactive oxygen species can activate pro-inflammatory signaling cascades and apoptotic pathways, which in turn exacerbate neuroinflammation, impair neurogenesis, and contribute to synaptic and structural changes implicated in depression (104)